Characterization of anti-microbials
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Classification Of Anti-microbials |
arrangement of anti-contamination retailers
A] primarily based on compound structureB] based on beginning
C] primarily based on scope of movement ( range of movement)
D] based totally on technique of pastime
E] based totally on impacts in their movement
F] based totally on path of agency
A] class of anti-toxins based totally on artificial structure:
1. Starch containing Antibiotics:2. Unadulterated saccharides anti-toxins: illustrations; Streptozotocin
3. Aminoglycosides: cases; Streptomycin
4. N/O glycosides: eg. Chromomycin
5. different: eg; Lincomycin
6. Macrocyclic lactone anti-toxins: eg. Erythromycin
7. Quinolones anti-toxins; eg. Fluroquinolone
8. N-containing heterocyclic anti-toxins: eg. Beta-lactum
9. O-containing heterocyclic anti-pollutants: eg. Cycloserine
10. Alicyclic anti-microbials: eg. Cycloheximide
11. aromatic anti-microbials (Nitrobenzene): eg. Chloramphenicol
12. Aliphatic amine anti-microbials: eg. Spermidine
13.Peptide anti-microbials: eg. Polymyxin, Bacitracin, Gramicidin
B] category of anti-microbials primarily based on motive:
1.Microbial cause:I. Bacterial cause:
Bacillus polymyxa: Polymyxin
Chromobacter violaceum: Bacitracin
Micromonospora spp: Gentamycin
ii. Parasitic reason:
Penicillium notatum: Penicillin
Cephalosporin spp: Cephalosporin
iii. Actimomycetes reason:
Streptomyces griseus: Streptomycin
S venezuelue:- Chloramphenicol
S erythreus:- Erythromycin
S mediterranae:- Rifampicin
2. Semi-engineered anti-microbials:
instances: Amoxycillin, Ampicillin, Doxycycline, Tigecycline, Sulfonamide and so on
3. Engineered anti-microbials:
cases: Chloramphenicol, 4-quinolones, Sulfonamide
C] class of anti-microbials based on scope of movement (range of action):
1.slender range:Dynamic in the direction of generally much less microorganisms.
instances: macrolides, Polymyxin
2. Direct variety:
Dynamic in the direction of Gram wonderful microscopic organisms and similarly some fundamental and UTI inflicting Gram bad microbes.
instances: Aminoglycosides, Sulfonamide
3. thin wide range:
Dynamic towards Gram superb and gram bad
cases: Beta-lactum
4. extensive variety:
Dynamic in opposition to Gram high quality and Gram terrible except for Pseudomonas and Mycobacteria.
instances: Chloramphenicol, Tetracycline
5. adverse to mycobacterial anti-infection agents:
cases: Ethambutol, Rifampicin, Isoniazid, Pyrazinamide
D] classification of anti-toxins based on Mode of activity:
1. Inhibitor of cell divider amalgamation/Peptidoglycan Inhibitors:cases:
Beta-lactum; Penicillin
Bacitracin
Cycloserine
Phosphomycin
Cephalosporin
Vancomycin
2. Inhibitor of protein amalgamation:
cases:
Streptomycin
Aminoglycosides
Fusidic corrosive
Antibiotic medicinal drug
Mupirocin
Chloramphenicol
Macrolides
3. Inhibitor of Nucleic corrosive amalgamation:
cases:
Quinolones
Ciprofloxacin
Nalidixic corrosive
Metronidazole
Nitrofurantoin
4. Inhibitor of folic corrosive amalgamation (Folate opposed)
instances:
Sulfonamide
Trimethoprim
5. Inhibitor of cytoplasmic layer:
cases:
Polymyxin; Colistin
E] classification of anti-toxins primarily based on affects of their movement:
1. Bactericidal:removes microscopic organisms
cases: Aminoglycosides, Penicillin, Cephalosporin
2. Bacteriostatic:
Represses the development of microorganisms
instances: Sulfonamide, antibiotic medicine, chloramphenicol, trimethoprim, macrolides, Lincosamide
F] classification of anti-pollution based totally on course of organization:
1. Oral anti-pollution:Corrosive strong anti-pollutants,
Illustrations; Penicillin V
2. Parenteral path:
Intravenous organization
Illustrations; Penicillin G
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